2021 2nd International Conference on Artificial Intelligence and Information Systems (ICAIIS 2021) will be held during May 28-30, 2021 in Chongqing, China. ICAIIS 2021 seeks to provide a high-level forum for experts, researchers, professionals, innovators and practitioners in the field of artificial intelligence and information systems from industry and academia to present and discuss the wide spectrum of original and novel researches and contributions together. Artificial intelligence and information systems are hotspot topics in modern academic and scientific field. It is an especially new research direction, so novel and state-of-the-art researches and inventions related to artificial intelligence and information systems emerge continuously. Besides, artificial intelligence and information systems can be widely applied in many fields, such as robot, decision-making, control system, simulation applications and so on. Therefore, ICAIIS 2021 will serve as a catalyst for explorations and discussion on new concepts and novel achievements of artificial intelligence and information systems from theoretical research and practical applications at the same time.